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Dr. Diana Fagan Professor Molecular Biology and Microbiology
330-941-1554 dlfagan AT ysu DOT edu WBSH 4015
B.S. University of Texas Medical Branch, 1976 Ph.D. University of Texas Southwestern Medical Center, 1986
Research Interests
Immune response to infectious disease Investigating new therapies for Staphylococcus aureus infections: 1. Production of monoclonal antibodies and development of diagnostic tests; 2. Production of carbohydrate mimetics to be tested for their ability to decrease capsule production and S. aureus infections.
Autologous mesenchymal stem cell transplantation to improve wound healing. Collaborative project with surgeons from St. Elizabeth Health Center.
Selected Publications
Marie, H., D. Fagan and J. Heffner. 2009. Biomechanical evaluation of autologous mesenchymal stem cell transplantation to improve fascial repair. Proceedings of the American Soc. Mechanical Eng.Volume 2: Biomedical and Biotechnology Engineering Paper no. IMECE2009-12466 pp. 97-100 doi:10.1115/IMECE2009-12466 .
Marie, H., Y. Zhang, J. Heffner, H.A. Dorian, D.L. Fagan. 2009. Biomechanical and elastographic analysi of wound healing using mesenchymal stromal cell treated tissue following surgery. J. Biomechanical Eng. July 2010 . Volume 132, Issue 7, 074503 (4 pages) doi:10.1115/1.4001382 .
Fagan D, Royal M, Vicarel M, Norris P. Carbohydrate mimetics as potential antiinfective treatments for Staphylococcus aureus The FASEB Journal. 2008:859.20.
Fagan D, Caldwell CC, and JA Smiley. Production of antibodies directed against Staphylococcus aureus serotype 8 capsular polysaccharide. 2004. FASEB J.
Fagan DL, EF Ervin, A Patel, K Khanna, VW Vanek and GD Niehaus. 2002. Human mononuclear cells exhibit circadian rhythm in expression of CD62L and CD54. Canadian Journal of Physiology and Pharmacology 80:935-940. |